Vaccines and therapeutics for immunocompromised patients with COVID-19

Shoham S, Batista C, Ben Amor Y, Ergonul O, Hassanain M, Hotez P, Kang G, Kim JH, Lall B, Larson HJ, Naniche D, Sheahan T, Strub-Wourgaft N, Sow SO, Wilder-Smith A, Yadav P, Bottazzi ME; Lancet Commission on COVID-19 Vaccines and Therapeutics Task Force. Vaccines and therapeutics for immunocompromised patients with COVID-19. EClinicalMedicine. 2023 May;59:101965. doi: 10.1016/j.eclinm.2023.101965. Epub 2023 Apr 12. PMID: 37070102; PMCID: PMC10091856.

Effectiveness of tocilizumab in non-intubated cases with COVID-19: a systematic review and meta-analysis

Keske Ş, Akyol M, Tanrıöver C, Özlüşen B, Akcan RE, Güler U, Sait B, Kaçmaz B, Gönen M, Ergönül Ö. Effectiveness of tocilizumab in non-intubated cases with COVID-19: a systematic review and meta-analysis. Infection. 2023 May 10:1–10. doi: 10.1007/s15010-023-02047-2. Epub ahead of print. PMID: 37162716; PMCID: PMC10170028.

Vaccines and therapeutics for immunocompromised patients with COVID-19

Shoham S, Batista C, Ben Amor Y, Ergonul O, Hassanain M, Hotez P, Kang G, Kim JH, Lall B, Larson HJ, Naniche D, Sheahan T, Strub-Wourgaft N, Sow SO, Wilder-Smith A, Yadav P, Bottazzi ME; Lancet Commission on COVID-19 Vaccines and Therapeutics Task Force. Vaccines and therapeutics for immunocompromised patients with COVID-19. EClinicalMedicine. 2023 May;59:101965. doi: 10.1016/j.eclinm.2023.101965. Epub 2023 Apr 12. PMID: 37070102; PMCID: PMC10091856.

Update of ESCMID COVID-19 guidelines: diagnostic testing for SARS-CoV-2

Paraskevi C. Fragkou, Giulia De Angelis, Giulia Menchinelli, Fusun Can, Federico Garcia, Florence Morfin-Sherpa, Dimitra Dimopoulou, Konstantina Dimopoulou, Silvia Zelli, Adolfo de Salazar, Rieke Reiter, Hannah Janocha, Adriano Grossi, Jimmy Omony, Chrysanthi Skevaki, Update of ESCMID COVID-19 guidelines: diagnostic testing for SARS-CoV-2,2023, https://doi.org/10.1016/j.cmi.2023.04.019.

COVID-19-associated mucormycosis: A systematic review and meta-analysis of 958 cases

Özbek L, Topçu U, Manay M, Esen BH, Bektas SN, Aydın S, Özdemir B, Khostelidi SN, Klimko N, Cornely O, Zakhour J, Kanj SS, Seidel D, Hoenigl M, Ergönül Ö. COVID-19-associated mucormycosis: A systematic review and meta-analysis of 958 cases. Clin Microbiol Infect. 2023 Mar 13:S1198-743X(23)00122-2. doi: 10.1016/j.cmi.2023.03.008. Epub ahead of print. PMID: 36921716; PMCID: PMC10008766.

Clinical evaluation of DIAGNOVIR SARS-CoV-2 ultra-rapid antigen test performance compared to PCR-based testing

Seymen AA, Gulten E, Ozgur E, Ortaç B, Akdemir I, Cinar G, Saricaoglu EM, Guney-Esken G, Akkus E, Can F, Karahan ZC, Azap A, Tuncay E. Clinical evaluation of DIAGNOVIR SARS-CoV-2 ultra-rapid antigen test performance compared to PCR-based testing. Sci Rep. 2023 Mar 17;13(1):4438. doi: 10.1038/s41598-023-31177-8. PMID: 36932107; PMCID: PMC10021059.

The association between Acinetobacter baumannii infections and the COVID-19 pandemic in an intensive care unit

Boral J, Genç Z, Pınarlık F, Ekinci G, Kuskucu MA, İrkören P, Kapmaz M, Tekin S, Çakar N, Şentürk E, Yurdakul F, Dikenelli B, Can F, Ergonul O. The association between Acinetobacter baumannii infections and the COVID-19 pandemic in an intensive care unit. Sci Rep. 2022 Dec 2;12(1):20808. doi: 10.1038/s41598-022-25493-8. PMID: 36460749; PMCID: PMC9716169.

Role of institutional, cultural and economic factors in the effectiveness of lockdown measures.

Çakmaklı C, Demiralp S, Ergönül Ö, Yeşiltaş S, Yıldırım MA. Role of institutional, cultural and economic factors in the effectiveness of lockdown measures. Int J Infect Dis. 2022 Mar;116:111-113. doi: 10.1016/j.ijid.2021.12.333. Epub 2021 Dec 23. PMID: 34954312; PMCID: PMC8765763.

A multinational Delphi consensus to end the COVID-19 public health threat.

Lazarus, J.V., Romero, D., Kopka, C.J. et al. A multinational Delphi consensus to end the COVID-19 public health threat. Nature 611, 332–345 (2022). doi:10.1038/s41586-022-05398-2386

Plasma proteomics identify potential severity biomarkers from COVID-19 associated network

Sahin AT, Yurtseven A, Dadmand S, Ozcan G, Akarlar BA, Kucuk NEO, Senturk A, Ergonul O, Can F, Tuncbag N, Ozlu N. Plasma proteomics identify potential severity biomarkers from COVID-19 associated network. Proteomics Clin Appl. 2022 Oct 11:e2200070. doi: 10.1002/prca.202200070. Epub ahead of print. PMID: 36217943.

Alterations in Vaginal Microbiota among Pregnant Women with COVID-19.

Celik E, Ozcan G, Vatansever C, Paerhati E, Kuşkucu MA, Dogan O, Cekic SG, Ergonul O, Gürsoy A, Keskin Ö, Can F. Alterations in Vaginal Microbiota among Pregnant Women with COVID-19. J Med Virol. 2022 Sep 6. doi: 10.1002/jmv.28132. Epub ahead of print. PMID: 36068653.

Protein Scaffold-Based Multimerization of Soluble ACE2 Efficiently Blocks SARS-CoV-2 Infection In Vitro and In Vivo

Kayabolen A, Akcan U, Özturan D, Ulbegi-Polat H, Sahin GN, Pinarbasi-Degirmenci N, Bayraktar C, Soyler G, Sarayloo E, Nurtop E, Ozer B, Guney-Esken G, Barlas T, Yildirim IS, Dogan O, Karahuseyinoglu S, Lack NA, Kaya M, Albayrak C, Can F, Solaroglu I, Bagci-Onder T. Protein Scaffold-Based Multimerization of Soluble ACE2 Efficiently Blocks SARS-CoV-2 Infection In Vitro and In Vivo. Adv Sci (Weinh). 2022 Jul 27:e2201294. doi: 10.1002/advs.202201294. Epub ahead of print. PMID: 35896894.

Duration of infectious shedding of SARS-CoV-2 omicron variant and its relation with symptoms

Keske Ş, Esken GG, Vatansever C, Beşli Y, Kuloğlu ZE, Nergiz Z, Barlas T, Şencanlı Ö, Kuşkucu MA, Palaoğlu E, Can F, Ergönül Ö. Duration of infectious shedding of SARS-CoV-2 omicron variant and its relation with symptoms. Clin Microbiol Infect. 2022 Jul 16:S1198-743X(22)00373-1. doi: 10.1016/j.cmi.2022.07.009. Epub ahead of print. PMID: 35853589; PMCID: PMC9287585.

COVID-19 Severity among Healthcare Workers: Overweight Male Physicians at Risk

Madran B, Akbulut Z, Akbaba G, Taş E, Güçlüoğlu T, Şencanlı Ö, Bozkurt İ, Keske Ş, Ergönül Ö. COVID-19 Severity among Healthcare Workers: Overweight Male Physicians at Risk. Infect Dis Rep. 2022 Apr 25;14(3):310-314. doi: 10.3390/idr14030036. PMID: 35645215; PMCID: PMC9149914.

Effect of BTN162b2 and Coronavac boosters on humoral and cellular immunity of individuals previously fully vaccinated with Coronavac against SARS-CoV-2: A longitudinal study

Kuloğlu ZE, El R, Guney-Esken G, Tok Y, Talay ZG, Barlas T, Kuskucu MA, Albayrak Ö, Doğan Ö, Yavuz SŞ, Midilli K, Ergönül Ö, Can F. Effect of BTN162b2 and Coronavac boosters on humoral and cellular immunity of individuals previously fully vaccinated with Coronavac against SARS-CoV-2: A longitudinal study. Allergy. 2022 Apr 19. doi: 10.1111/all.15316. Epub ahead of print. PMID: 35437772.

Inappropriate use of ivermectin during the COVID-19 pandemic: Primum non nocere!

Barac A, Bartoletti M, Azap O, et al. Inappropriate use of ivermectin during the COVID-19 pandemic: Primum non nocere! [published online ahead of print, 2022 Mar 22]. Clin Microbiol Infect. 2022;S1198-743X(22)00161-6. doi:10.1016/j.cmi.2022.03.022

ESCMID COVID-19 guidelines: diagnostic testing for SARS-CoV-2

Fragkou PC, De Angelis G, Menchinelli G, et al. ESCMID COVID-19 guidelines: diagnostic testing for SARS-CoV-2 [published online ahead of print, 2022 Feb 23]. Clin Microbiol Infect. 2022;S1198-743X(22)00084-2. doi:10.1016/j.cmi.2022.02.011

ESCMID COVID-19 living guidelines: drug treatment and clinical management: author’s reply

Bartoletti M, Azap O, Barac A, et al. ESCMID COVID-19 living guidelines: drug treatment and clinical management: author’s reply. Clin Microbiol Infect. 2022;28(4):617-618. doi:10.1016/j.cmi.2021.12.025

The silent and dangerous inequity around access to COVID-19 testing: A call to action

Batista C, Hotez P, Amor YB, et al. The silent and dangerous inequity around access to COVID-19 testing: A call to action. EClinicalMedicine. 2022;43:101230. doi:10.1016/j.eclinm.2021.101230

Placental deficiency during maternal SARS-CoV-2 infection

Celik E, Vatansever C, Ozcan G, et al. Placental deficiency during maternal SARS-COV-2 infection. Placenta. 2021. doi:10.1016/j.placenta.2021.10.012

Achieving global equity for COVID-19 vaccines: Stronger international partnerships and greater advocacy and solidarity are needed

Figueroa JP, Hotez PJ, Batista C, et al. Achieving global equity for COVID-19 vaccines: Stronger international partnerships and greater advocacy and solidarity are needed. PLoS Med. 2021;18(9):e1003772. Published 2021 Sep 13. doi:10.1371/journal.pmed.1003772

Immunogenicity after two doses of inactivated virus vaccine in healthcare workers with and without previous COVID-19 infection: Prospective observational study

Yalçın TY, Topçu DI, Doğan Ö, et al. Immunogenicity after two doses of inactivated virus vaccine in healthcare workers with and without previous COVID-19 infection: Prospective observational study [published online ahead of print, 2021 Sep 1]. J Med Virol. 2021;10.1002/jmv.27316. doi:10.1002/jmv.27316

Effect of High-Risk Obstructive Sleep Apnea on Clinical Outcomes in Adults with Coronavirus Disease 2019: A Multicenter, Prospective, Observational Clinical Trial

Peker Y, Celik Y, Arbatli S, et al. Effect of High-Risk Obstructive Sleep Apnea on Clinical Outcomes in Adults with Coronavirus Disease 2019: A Multicenter, Prospective, Observational Clinical Trial. Ann Am Thorac Soc. 2021;18(9):1548-1559. doi:10.1513/AnnalsATS.202011-1409OC

Global public health security and justice for vaccines and therapeutics in the COVID-19 pandemic

Hotez PJ, Batista C, Amor YB, et al. Global public health security and justice for vaccines and therapeutics in the COVID-19 pandemic. EClinicalMedicine. 2021;39:101053. doi:10.1016/j.eclinm.2021.101053

Risk Groups for SARS-CoV-2 Infection among Healthcare Workers: Community Versus Hospital Transmission

Pınarlık F, Genç Z, Kapmaz M, Tekin S, Ergönül Ö. Risk Groups for SARS-CoV-2 Infection among Healthcare Workers: Community Versus Hospital Transmission. Infect Dis Rep. 2021;13(3):724-729. Published 2021 Aug 13. doi:10.3390/idr13030067

Effectiveness of favipiravir in COVID-19: a live systematic review

Özlüşen B, Kozan Ş, Akcan RE, et al. Effectiveness of favipiravir in COVID-19: a live systematic review [published online ahead of print, 2021 Aug 4]. Eur J Clin Microbiol Infect Dis. 2021;1-9. doi:10.1007/s10096-021-04307-1

The Role of Obesity in Predicting the Clinical Outcomes of COVID-19

Sahin S, Sezer H, Cicek E, et al. The Role of Obesity in Predicting the Clinical Outcomes of COVID-19. Obes Facts. 2021;14(5):481-489. doi:10.1159/000517180

Machine learning detects SARS-CoV-2 and variants rapidly on DNA aptamer metasurfaces

Torun H, Bilgin B, Ilgu M, et al. Machine learning detects SARS-COV-2 and variants rapidly on DNA aptamer metasurfaces. 2021. doi:10.1101/2021.08.07.21261749

Effectiveness of different types of Masks in Aerosol Dispersion in SARS–CoV-2 Infection

Tanisali G, Sozak A, Bulut AS, Sander TZ, Dogan Ö, Dağ Ç, Gönen M, Can F, Demirci H, Ergönül Ö. Int J Infect Dis. 2021 June. doi:10.1016/j.ijid.2021.06.029.

The seroprevalence of SARS-CoV-2 antibodies among health care workers before the era of vaccination: a systematic review and meta-analysis

Kayı İ, Madran B, Keske Ş, Karanfil Ö, Arribas JR, Pshenichnaya N, Petrosillo N, Gönen M, Ergönül Ö. Clin Microniol Infect., 2021 June; doi: 10.1016/j.cmi.2021.05.036. Epub 2021 Jun 8. PMCID: PMC8186944. PMID: 34116205.

Beyond the jab: A need for global coordination of pharmacovigilance for COVID-19 vaccine deployment

Naniche D, Hotez P, Bottazzi ME, Ergonul O, Figueroa JP, Gilbert S, Gursel M, Hassanain M, Kang G, Kaslow D, Kim JH, Lall B, Larson H, Sheahan T, Shoham S, Wilder-Smith A, Sow SO, Strub-Wourgaft N, Yadav P, Batista C. EClinicalMedicine. 2021 Jun;36:100925. doi: 10.1016/j.eclinm.2021.100925. Epub 2021 Jun 3. PMID: 34099998; PMCID: PMC8173024.

Existence of SARS-CoV-2 RNA on ambient particulate matter samples: A nationwide study in Turkey

Kayalar Ö, Arı A, Babuççu G, Konyalılar N, Doğan Ö, Can F, Şahin ÜA, Gaga EO, Levent Kuzu S, Arı PE, Odabaşı M, Taşdemir Y, Sıddık Cindoruk S, Esen F, Sakın E, Çalışkan B, Tecer LH, Fıçıcı M, Altın A, Onat B, Ayvaz C, Uzun B, Saral A, Döğeroğlu T, Malkoç S, Üzmez ÖÖ, Kunt F, Aydın S, Kara M, Yaman B, Doğan G, Olgun B, Dokumacı EN, Güllü G, Uzunpınar ES, Bayram H. Sci Total Environ. 2021 May 25;789:147976. doi: 10.1016/j.scitotenv.2021.147976. Epub ahead of print. PMID: 34058581; PMCID: PMC8144095.

Urgent needs to accelerate the race for COVID-19 therapeutics

Presence of Severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) RNA on Particulate Matters: A Multi Central Study in Turkey

Bayram H, Kayalar Ö, Arı A, Babuççu G, Konyalılar N, Doğan Ö, Can F, Gaga E, Kuzu L, Arı P, Odabaşı M, Taşdemir Y, Cindoruk S, Esen F, Sakin E, Calışkan B, Tecer L, Fıçıcı M, Altın A, Onat B, Ayvaz C, Kara M, Yaman B, Doğan G, Olgun B, Dokumacı E, Güllü G, Uzunpınar E, Şahin Ü. Am J Respir Crit Care Med. 2021 May; 203:A3080-A3080. doi: 10.1164/ajrccm-conference.2021.203.1_MeetingAbstracts.A3080

Operation Warp Speed: implications for global vaccine security

Lancet Commission on COVID-19 Vaccines and Therapeutics Task Force Members. Lancet Glob Health. 2021 Jul;9(7):e1017-e1021. doi: 10.1016/S2214-109X(21)00140-6. Epub 2021 Mar 26. PMID: 33780663; PMCID: PMC7997645.

Correcting COVID-19 vaccine misinformation: Lancet Commission on COVID-19 Vaccines and Therapeutics Task Force Members

Hotez P, Batista C, Ergonul O, Figueroa JP, Gilbert S, Gursel M, Hassanain M, Kang G, Kim JH, Lall B, Larson H, Naniche D, Sheahan T, Shoham S, Wilder-Smith A, Strub-Wourgaft N, Yadav P, Bottazzi ME.  EClinicalMedicine. 2021 Mar;33:100780. doi: 10.1016/j.eclinm.2021.100780. Epub 2021 Mar 6. PMID: 33718854; PMCID: PMC7935671.

Is elective cancer surgery feasible during the lock-down period of the COVID-19 pandemic? Analysis of a single institutional experience of 404 consecutive patients

Kulle CB, Azamat IF, Vatansever D, Erus S, Tarim K, Akyoldas G, Gokler O, Deveci MA, Cakar N, Ergonul O, Agcaoglu O, Kiremit MC, Yavuz O, Kiris T, Unsaler S, Giray B, Korkmaz M, Dilege E, Kilic M, Cesur E, Solaroglu I, Altuntas O, Simsek A, Tanju S, Erkan M, Canda E, Sasani M, Hafiz AM, Kordan Y, Balik E, Bilge O, Bugra D, Taskiran C, Dilege S.  J Surg Oncol. 2021 Jun;123(7):1495-1503. doi: 10.1002/jso.26436. Epub 2021 Feb 23. PMID: 33621377; PMCID: PMC8013582.

What is the ‘new normal’ in surgical procedures in the era of COVID-19?

Cimen C, Keske Ş, Ergönül Ö. Clin Microbiol Infect. 2021 Jan;27(1):16-18. doi: 10.1016/j.cmi.2020.09.038. Epub 2020 Sep 30. PMID: 33007477; PMCID: PMC7525368.

Physical rehabilitation in intensive care unit in acute respiratory distress syndrome patients with COVID-19

Ozyemisci Taskiran O, Turan Z, Tekin S, Senturk E, Topaloglu M, Yurdakul F, Ergonul O, Cakar N. Eur J Phys Rehabil Med. 2021 Jan 15. doi: 10.23736/S1973-9087.21.06551-5. Epub ahead of print. PMID: 33448757.

Protein scaffold-based multimerization of soluble ACE2 efficiently blocks SARS-CoV-2 infection in vitro

Kayabolen A, Akcan U, Özturan D, Sarayloo E, Nurtop E, Özer B, Sahin GN, Doğan Ö, Lack N, Kaya M, Albayrak C, Can F, Solaroğlu İ, Bağcı-Önder T. BioRvix. Preprint posted online 2021 Jan. doi: 10.1101/2021.01.04.425128

Urgent needs of low-income and middle-income countries for COVID-19 vaccines and therapeutics

Lancet Commission on COVID-19 Vaccines and Therapeutics Task Force Members. Lancet. 2021 Feb 13;397(10274):562-564. doi: 10.1016/S0140-6736(21)00242-7. Epub 2021 Jan 28. PMID: 33516284; PMCID: PMC7906712.

Molecular Communication Theoretical Modeling and Analysis of SARS-CoV2 Transmission in Human Respiratory System

Koca C, Civas M, Sahin SM, Ergonul O, Akan OB. IEEE Transactions on Molecular, Biological, and Multi-Scale Communications. 2021 Oca 1. https://doi.org/10.1109/TMBMC.2021.3071748

Infectivity of Adult and Pediatric COVID-19 Patients

Kapmaz M, Doğan Ö, Aktürk H, Özer B, Nurtop E, Vatansever C, Özcan G, Çelikyurt A, Khalilova F, Okan A, İncir S, Sackesen C, Ergönül Ö, Can F. ResearchSquare. Preprint posted online 2020 Dec. doi: 10.21203/rs.3.rs-114148/v1.

Influenza vaccination among infection control teams: A EUCIC survey prior to COVID-19 pandemic

Keske Ş, Mutters NT, Tsioutis C, Ergönül Ö; EUCIC Vaccine. 2020 Dec 14;38(52):8357-8361. doi: 10.1016/j.vaccine.2020.11.003. Epub 2020 Nov 5. PMID: 33183855.

Why we should be more careful using hydroxychloroquine in influenza season during COVID-19 pandemic?

Çelik HG, Keske Ş, Şener Ü, Tekbaş M, Kapmaz M, Şahin ŞT, Özyıldırım A, Aytekin S, Aytekin V, Ergönül Ö. Int J Infect Dis. 2021 Jan;102:389-391. doi: 10.1016/j.ijid.2020.10.080. Epub 2020 Oct 29. PMID: 33130195; PMCID: PMC7834514.

What Can We Estimate From Fatality and Infectious Case Data Using the Susceptible-Infected-Removed (SIR) Model? A Case Study of Covid-19 Pandemic

Ahmetolan S, Bilge AH, Demirci A, Peker-Dobie A, Ergonul O.Front Med (Lausanne). 2020 Sep 3;7:556366. doi: 10.3389/fmed.2020.556366. PMID: 33015109; PMCID: PMC7494820.

National case fatality rates of the COVID-19 pandemic

Ergönül Ö, Akyol M, Tanrıöver C, Tiemeier H, Petersen E, Petrosillo N, Gönen M. Clin Microbiol Infect. 2021 Jan;27(1):118-124. doi: 10.1016/j.cmi.2020.09.024. Epub 2020 Sep 23. PMID: 32979575; PMCID: PMC7510430.

Appropriate use of tocilizumab in COVID-19 infection

Keske Ş, Tekin S, Sait B, İrkören P, Kapmaz M, Çimen C, Uğur S, Çelebi İ, Bakır VO, Palaoğlu E, Şentürk E, Çağlayan B, Çakar N, Tabak L, Ergönül Ö.Int J Infect Dis. 2020 Oct;99:338-343. doi: 10.1016/j.ijid.2020.07.036. Epub 2020 Jul 26. PMID: 32726724; PMCID: PMC7382959.